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Mepolizumab -- therapeutic strategy for a paediatric patient with eosinophilic granulomatosis with polyangiitis
  • +5
  • Lota Ozola,
  • Elīna Aleksejeva,
  • Diāna Stoldere,
  • Ineta Grantiņa,
  • Zane Dāvidsone,
  • Ruta Šantere,
  • Ieva Cīrule,
  • Alvils Krams
Lota Ozola
Bērnu klīniskā universitātes slimnīca

Corresponding Author:lota.ozola@bkus.lv

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Elīna Aleksejeva
Bērnu klīniskā universitātes slimnīca
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Diāna Stoldere
Bērnu klīniskā universitātes slimnīca
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Ineta Grantiņa
Bērnu klīniskā universitātes slimnīca
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Zane Dāvidsone
Bērnu klīniskā universitātes slimnīca
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Ruta Šantere
Bērnu klīniskā universitātes slimnīca
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Ieva Cīrule
Bērnu klīniskā universitātes slimnīca
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Alvils Krams
Rīgas Austrumu klīniskā universitātes slimnīca
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Abstract

Eosinophilic granulomatosis with polyangiitis (EGPA; formerly known as Churg-Strauss syndrome) is classified as an anti-neutrophil cytoplasmic antibody (ANCA)-associated small vessel vasculitis. It is a multisystem disorder and can affect every organ system. EGPA is a rare disease, with an estimated prevalence of 1/70,000–100,000 in Europe. As its onset usually occurs in adulthood, data from paediatric patients are limited. We present here a very rare practical EGPA clinical case involving a paediatric patient. Presently, data on mepolizumab usage in paediatric patients are limited, with only a few case reports published.
11 Jan 2022Submitted to Pediatric Pulmonology
12 Jan 2022Submission Checks Completed
12 Jan 2022Assigned to Editor
12 Jan 2022Reviewer(s) Assigned
11 Feb 2022Review(s) Completed, Editorial Evaluation Pending
12 Feb 2022Editorial Decision: Revise Major
14 Jul 20221st Revision Received
28 Aug 2022Submission Checks Completed
28 Aug 2022Assigned to Editor
28 Aug 2022Reviewer(s) Assigned
04 Oct 2022Review(s) Completed, Editorial Evaluation Pending
05 Oct 2022Editorial Decision: Revise Minor
16 Oct 20222nd Revision Received
17 Oct 2022Assigned to Editor
17 Oct 2022Review(s) Completed, Editorial Evaluation Pending
17 Oct 2022Submission Checks Completed
17 Oct 2022Reviewer(s) Assigned
06 Nov 2022Editorial Decision: Accept