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Coronavirus 19 (COVID-19) infection and vaccination in patients with Shwachman-Diamond syndrome
  • +2
  • Thomas Galletta,
  • Sara Loveless,
  • Maggie Malsch,
  • Akiko Shimamura,
  • Kasiani Myers
Thomas Galletta
Cincinnati Children's Hospital Medical Center
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Sara Loveless
Cincinnati Children's Hospital Medical Center
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Maggie Malsch
Boston Children's Hospital
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Akiko Shimamura
Dana-Farber/Boston Children's Cancer and Blood Disorders Center
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Kasiani Myers
Cincinnati Children's Hospital Medical Center
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Abstract

Because they can experience neutropenia due to bone marrow failure, patients with Shwachman-Diamond syndrome (SDS) carry increased risk for serious infections compared to the general population; however, it has been unknown whether this predisposes them to COVID-19 infection or more significant complications. We compiled results from a survey distributed to participants in the Shwachman-Diamond Syndrome Registry between May and June 2021. In this report we describe the characteristics and outcomes of patients with SDS who had COVID-19. Patients reported a short clinical course without significant complications or severe cytopenias. Additionally, COVID-19 vaccines were well tolerated with only minor side effects.
29 Dec 2021Submitted to Pediatric Blood & Cancer
29 Dec 2021Submission Checks Completed
29 Dec 2021Assigned to Editor
31 Dec 2021Reviewer(s) Assigned
09 Jan 2022Review(s) Completed, Editorial Evaluation Pending
17 Jan 2022Editorial Decision: Revise Minor
01 Feb 2022Submission Checks Completed
01 Feb 2022Assigned to Editor
01 Feb 20221st Revision Received
07 Feb 2022Reviewer(s) Assigned
12 Feb 2022Review(s) Completed, Editorial Evaluation Pending
22 Feb 2022Editorial Decision: Accept