loading page

Short-term results of percutaneous closure of patent foramen ovale guided by transoesophageal echocardiography in patients with cryptogenic stroke: A retrospective study
  • +5
  • Yilong Guo,
  • Zhensu Shi,
  • Yin Zheng,
  • Caichan Xie,
  • Jiao Yi,
  • Zelun Chen,
  • Yue Shu,
  • Dexing Zhou
Yilong Guo
Medical School of Chinese PLA Beijing People’s Republic of China
Author Profile
Zhensu Shi
Department of Cardiovascular Surgery The Second Affiliated Hospital of Hainan Medical University Haikou Hainan People’s Republic of China
Author Profile
Yin Zheng
Department of Special Medical Services Hainan Cancer Hospital Haikou Hainan People’s Republic of China
Author Profile
Caichan Xie
Department of Cardiovascular Surgery The Second Affiliated Hospital of Hainan Medical University Haikou Hainan People’s Republic of China
Author Profile
Jiao Yi
Department of Cardiovascular Surgery The Second Affiliated Hospital of Hainan Medical University Haikou Hainan People’s Republic of China
Author Profile
Zelun Chen
Department of Cardiovascular Surgery The Second Affiliated Hospital of Hainan Medical University Haikou Hainan People’s Republic of China
Author Profile
Yue Shu
Department of Cardiovascular Surgery The Second Affiliated Hospital of Hainan Medical University Haikou Hainan People’s Republic of China
Author Profile
Dexing Zhou
Department of Cardiovascular Surgery The Second Affiliated Hospital of Hainan Medical University Haikou Hainan People’s Republic of China
Author Profile

Abstract

Background: This study aimed to assess the short-term (12 months) results of PFO occlusion guided by transoesophageal echocardiography (TEE) and the results of regular transthoracic ultrasound foaming test (UFT). Methods: Data of 75 patients who underwent interventional therapy for PFO and CS were retrospectively analysed. The patients were grouped according to their preoperative UFT results: group A, small volume of right-to-left shunts; group B, moderate volume of right-to-left shunts; and group C, large volume of right-to-left shunts. All patients were treated with an Amplatzer occluder under TEE guidance. UFT follow-up was conducted regularly until 12 months after surgery. Results: No remarkable differences in preoperative data, length of hospital stay, or operative time were noted between the groups. Length of the PFO and diameter of the occluder differed between the groups: group A=group Bp<0.001). One patient in group C developed recurrent stroke 11 months postoperatively. Two patients in group C developed atrial arrhythmia, which improved after 3 months of antiarrhythmic treatment. However, 19 patients still had positive UFT results 12 months postoperatively. Furthermore, the positive UFT rate 12 months postoperatively differed between the groups: group A=group Bp<0.05). Conclusions: In patients with PFO and CS, interventional therapy guided by TEE could lead to satisfactory short-term (12 months) outcomes. A longer PFO and preoperative large-volume shunt were negatively associated with a negative UFT rate 12 months postoperatively. Further studies are required to clarify the relationship between positive UFT results postoperatively and stroke recurrence.